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Until more robust evidence emerges, clinical decisions must be individualised, weighing the theoretical risks of reduced absorption against the patient's preferences, diabetes control, and alternative treatment options
It did inhibit appetite and food intake in people
GIP receptor activation further augments insulin secretion and is proposed to influence lipid metabolism and energy expenditure, though these effects are not fully established in humans
The price of Ozempic, which is semaglutide approved for type 2 diabetes, can cost as little as $25/month with insurance when it is prescribed for diabetes, but often it is not covered at all when prescribed off label for weight loss