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Bone deformation and osteopathy can also occur.[ref] There are three types of primary hyperoxaluria: [ref] Primary hyperoxaluria type 1 is caused by a mutation in the AGXT gene , which causes a deficiency in the bodys ability to metabolize glyoxylate into other compounds

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[ref][ref] Oxalate-induced arthritis, or joint inflammation due to oxalates, is caused by the deposition of sharp calcium oxalate crystals in the synovial fluid that surrounds a joint

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