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However, there are cases of individuals exhibiting symptoms even though they are heterozygous for a single pathogenic variant allele

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Basu M, Pal K, Prasad R, Malhotra AS, Rao KS, Sawhney RC

Journal of Agricultural and Food Chemistry, 55(16), 64666474

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Additionally, TB-500 presentation following alkali injury may reduce the expression of chemoattractants for polymorphonuclear neutrophils (PMNs), MIP-2, and KC in mouse corneas, possibly resulting in reduced PMN infiltration