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When the conversion of propionyl-CoA to succinyl-CoA in the mitochondria fails due to Vitamin B 12 deficiency, elevated blood levels of methylmalonic acid (MMA) occur

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However, phosphatase enzymes hydrolytically remove phosphate groups, effectively reversing the regulatory effects of the kinases

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As part of selenoproteins, Se takes an active part in antioxidant, redox and anti-inflammatory processes (59)