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Pernicious anemia is an autoimmune condition that happens when your immune system produces antibodies that attack cells in the mucosal lining of your stomach and nerve cells

LeWine, MD, Chief Medical Editor, Harvard Health Publishing

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Ranging from serious (medical) to minor (diet), these absorption and storage issues stem from a variety of reasons

By blocking NNMT activity, 5-amino-1MQ preserves intracellular NAD+ availability, which activates sirtuins and the AMPK pathway

Vitamin B12 functions as a cofactor for two essential enzymes: methionine synthase (involved in homocysteine metabolism and DNA synthesis) and methylmalonyl-CoA mutase (crucial for fatty acid and amino acid metabolism)