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Of note, although inhibition of PPAR diminished the glucose-lowering effect of GLP-1GIPLani, antagonization of PPAR did not ameliorate weight loss induced by either GLP-1GIPLani or the selective PPAR agonist GW501516 (Fig

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We performed a network meta-analysis to compare the effect on cardiorenal outcomes among GLP-1 RAs, SGLT-2 inhibitors and dipeptidyl peptidase-4 (DPP-4) inhibitors

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It occurs because GLP-1 medications slow how quickly the stomach empties, causing food to stay in the stomach longer

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