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There are many risk factors involved in infertility issues but the main ones are the following: age fertility declines with age, weight being overweight or underweight, sexually transmitted infections (STIs), smoking, alcohol, STRESS, environmental factors, PCOS, endometriosis, and certainly genetics

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A potent CysLT1 receptor antagonist, montelukast inhibits the activation of the NF-B pathway and secretion of IL-6 and IL-8 in FLS (165), next to reducing the disease incidence and its activity (166)