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Diabetes (2012) 61:292300

Subsequent multiple linear regression analysis, using muscle mass loss as the dependent variable and Semaglutide dosage, baseline ASMI, handgrip strength, and gait speed as independent variables, confirmed independent associations for semaglutide dosage, baseline ASMI, and gait speed, whereas handgrip strength lost statistical significance

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Furthermore, mitochondrial dysfunction, neuroinflammation, and oxidative stress are central to biochemical events in PD such as S aggregation, dysregulated sirtuin activity, and impaired insulin signaling (Picca et al., 2020)

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