Patients should only use medications prescribed by their healthcare professional and should not attempt to source unlicensed transdermal products, in line with MHRA guidance on buying medicines safely
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Theres also evidence that de-escalation of dosing that is, spacing out the doses to every other week or longer, or reducing the dose may help people keep the weight off once they are in the maintenance phase
Gibbons et al., studied the effect of oral semaglutide in 15 subjects with type 2 diabetes and reduction on appetite and craving, demonstrating not just the reduction in calorie intake, but also lowering the palatability and preference for sweet and high fat food (177)