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In alcoholic liver diseases, the role of the gut-brain axis should also be taken into account since anxiety and depression are usually coupled with excessive alcohol consumption (98)

doi: 10.1002/CBDV.202300924 183 Urban-ChmielR.MarekA.Stpie-PyniakD.WieczorekK.DecM.NowaczekA.et al

This can come from general wear-and-tear , where years of use may eventually catch up to you and cause pain that seems to come from out of nowhere, without injury

This healing effect is observed in various models of corneal injury, including perforating corneal incisions