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Statements Author contributions BH wrote the manuscript

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This does not replace hormonal therapy when it is clinically indicated

doi:10.1016/s2213-8587(21)00295-3 190

Studies confirm that overexpression of enzymes in sulfate assimilation, GSH or PC biosynthesis have led to enhanced metal accumulation and tolerance to different metals [36,8083]

They enrolled adults aged 55 to 85 with mild cognitive impairment or mild dementia due to Alzheimers disease, confirmed by amyloid status, and tested once-daily oral semaglutide against placebo on top of standard care