Six weeks of GLP-1 infusion resulted in significant improvements in fasting (decrease of 4.3 mM glucose) and 8 h mean glucose (decrease of 5.5 mM), fasting and mean 8h free fatty acids, a reduction in HbA1c from 9.2% to 7.9%, a decrease in fructosamine from 349 uM to 282 uM, and a reduction in gastric emptying 3,4
Appetite suppression timing varies, and some people require higher doses or longer treatment duration
Because these pathways work gradually, changes are often noticed over weeks rather than days, especially for skin and hair goals
doi: 10.1016/j.canlet.2015.07.026 174 GoelHLFornaroMMoroLTeiderNRhimJSKingMet al
After 8 weeks, there were no significant differences between groups in change of muscle strength
Cagrilintide acts through amylin pathways