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Spann said that needs to change

Typically self-administered as a simple, subcutaneous injection

As previously discussed, PE is an adhesin of NTHi with functions involved in haem binding, storage and inter-bacterial donation (Duell et al., 2016)

Therefore, the sponsors concluded that clinically significant DDIs mediated by direct inhibition of CYP enzymes or transporters are unlikely to occur with the administration of GLP-1 RAs and a dual GLP-1/GIP RA

This stands in contrast to the hepatotoxicity that terminated Pfizer's danuglipron and lotiglipron programs

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