The risk-benefit calculation strongly favors semaglutide for most patients, particularly those with existing cardiovascular risk factors
Patients should work with registered dietitians to establish sustainable eating patterns before discontinuation
Benefits of Semaglutide Semaglutide helps manage type 2 diabetes by improving blood sugar levels and lowering the risk of significant cardiovascular events
Reverse research inducing cirrhosis in mice showed that cirrhosis leads to dysfunction of the intestinal barrier, and found that FXR agonists can ameliorate the translocation of gut bacteria to the liver by restoring the integrity of the gut-vascular barrier (Sorribas et al., 2019)
The anti-AS effects of GLP-1RAs include the regulation of inflammation (109), reduction of intima-media thickening (120), improvement of blood lipid profile (121), and regulation of endothelial dysfunction (122)
Many patients can achieve a more significant weight loss and further reduce health concerns like prediabetes, heart disease, high cholesterol, hypertension, or obstructive sleep apnea