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It is established that anhedonia is caused by the inflammatory stimuli [14] affecting the neurotransmitters and neurocircuits involved in reward processing, including the ventral striatum and ventromedial prefrontal cortex [15]

Individual goals and preferences influence the choice between the two approaches

2 Torres-Mora J, Dry S, Li X, Binder S, Amin M, Folpe AL

Initial preclinical and clinical studies have demonstrated ARA-290s broad therapeutic potential, particularly in conditions characterized by inflammation, tissue damage, and neuropathy

Bowel changes, either constipation or loose stools, affect roughly 20 percent of users initially