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By inhibiting NNMT, 5-Amino-1MQ preserves SAM availability and reduces SAH accumulation, potentially supporting proper methylation of DNA, histones, and proteins - epigenetic modifications that regulate gene expression and cellular function

Poormasjedi-Meibod M-S, Hartwell R, Kilani RT, Ghahary A

Craniosynostosis is a condition that occurs when one or more of the fibrous joints between a babys skull bones, called sutures, close prematurely before the brain is fully formed

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doi: 10.1007/s00408-021-00465-3 36 CecchiniR.CecchiniA