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Furthermore, mutations in NKX2-5 [77] and TBX5 [78] cause CCD in association with congenital heart disease

Individuals with confirmed B12 deficiency due to dietary insufficiency may benefit from oral B12 supplementation (including sublingual forms)

Applied to the two compounds here, the framework is clarifying

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Vitamins contain essential micronutrients that are needed for normal cell function, growth, and development