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J Neurosci 20(18):69206926
Estimates of the effects of SGLT2is and GLP-1 RAs on cardiovascular and kidney disease and all-cause mortality were assumed to be class effects and were thus drawn from the recent meta-analyses of major-outcomes trials [2,3,4]
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That magnitude is exactly why the muscle question matters: the more total weight you lose, the more total lean mass rides along with it
Many patients find success by splitting their total daily dose into two or three smaller doses (e.g., morning, afternoon, and night) to provide a steady, continuous stream of autonomic and immunological support throughout the day
