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"These guidelines will help all providers who care for patients treated with immune checkpoint inhibitors, not just oncologists, but also emergency room and primary care doctors, assess and manage these side effects." Key guideline recommendations: In general, checkpoint inhibitors can be continued with close monitoring for mild (grade 1) toxicities, with the exception of neurologic and some hematologic toxicities

High levels of BCAAs or branched alpha-ketoacids reduce the total antioxidant capacity of cells and significantly increase the production of lipid peroxidation products

doi: 10.7150/thno.9265 83 HeXde SeymourJVSulekKQiHZhangHHanT-Let al

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