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doi: 10.1038/nrgastro.2016.169 49 BeumerJCleversH

We also discuss long-term implications for T2DM care, weight management and, ultimately, cardiorenal disease prevention in patients with T2DM and/or overweight or obesity

The alternative it describes is fewer, denser, higher-protein meals with lower total volume, adjusted according to training phase rather than kept the same year-round

Rapid or significant weight loss can cause facial volume loss, hollowing of the cheeks and deeper lines, giving the face a more tired appearance

Most users feel a clear lift within days

Others return to baseline eating habits unintentionally