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21 If you have reduced HNMT activity, you're more likely to accumulate intracellular histamine, which means even if your DAO is working fine in the gut, you may still have problems clearing histamine in your brain (contributing to brain fog, nervousness, sleep issues) and airways (contributing to respiratory symptoms)

Hydrogen peroxide- and glutathione-associated mechanisms of acclimatory stress tolerance and signalling

92 In another study on tumor metabolism, Sullivan et al

It actually helps detoxify the liver and protect it from damage