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Despite glucagons blood sugar-increasing effect, glucagon receptor activation moderates food intake, enhances fatty acid breakdown, and increases energy expenditure, supporting the rational use of glucagon in combination with other incretin hormones in the treatment of obesity and T2DM [34]

GLP-1RAs might have a direct impact on keratinocytes, as evidenced by the detection of GLP-1R and glucagon in neonatal mouse skin and cultured skin cells [203]

It may also boost energy levels and cognitive function and improve insulin sensitivity

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Proper consultation and the right approach are needed to effectively treat the area