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Larger, well-designed clinical trials are needed to establish definitive recommendations, and current UK guidance does not support routine use

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Our RNA-seq data demonstrated increased expression of key components in the p38/JNK MAPK pathway ( pmk-1, pmk-3, mek-1, sek-1 ) under mrps-5 RNAi, which were reversed when mrps-5 is double-knocked down with C32E8.9