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Mice from a different substrain and vendor, but fed similar lean and high-fat diets to this study, showed a predominance of the family Erysipelotrichaceae, of which Ileibacterium is a genus, in their cecal microbiomes 76

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Like the peptides themselves, however, the combinations of agents have not been well studied

Key Insight: With no energy improvements by week 4, bloodwork can help assess whether NNMT is being effectively inhibited

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