The animals' feeding area and water troughs were cleaned regularly to prevent contamination
Glutathione IV (intravenous) therapy involves administering this powerful antioxidant directly into the bloodstream for enhanced bioavailability
Autophagy defects lead to the accumulation of depolarized mitochondria and proteins and induce the release of inflammatory body activator (ROS or mitochondrial DNA) [92, 93]
Duration:45 minutes D-ALA (Alpha Lipoic Acid) IV treatment delivers powerful antioxidant benefits by neutralizing free radicals and reducing oxidative stress
The treatment regimen included a preventive dose 60 15 minutes prior to MCAO, followed by daily doses for 7 days after reperfusion
Marin B, Bianchi E, Pupillo E, Lunetta C, Tremolizzo L, Logroscino G, Chi A, Preux PM, Beghi E (2015) Non-self-sufficiency as a primary outcome measure in ALS trials