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81 A study in anxious dogs showed treatment with the probiotic yeast Saccharomyces boulardii, at 1 billion CFUs per kg of dog food daily for 35 days, decreased levels of cortisol, suggesting stress reduction

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4 GLP-1RAs (eg, tirzepatide, semaglutide, and liraglutide) are synthetic peptides that mimic endogenous GLP-1, and use of these therapies has expanded beyond their metabolic functions in type 2 diabetes and weight loss into other diseases due to their anti-inflammatory properties and their ability to modulate immune function

13,66 Cellular-wise, the enzyme spans all intracellular organelles and compartments, including transmembrane areas, and is secreted extracellularly