The synergistic effect of nutritional-related metabolic syndrome on OA Beyond obesity alone, the constellation of nutrition-related metabolic syndrome (MetS) components including insulin resistance, dyslipidemia, and hyperglycemia, synergistically exacerbates OA progression through interconnected pathways
To our awareness, this is the original work that confirmed the effect of Dula in decreasing the elevated levels of PI3K and AKT in a rat model of AA-induced colitis
Extrahepatic malignancies - particularly colorectal, breast, and pancreatic cancer - are more common in MASLD patients independent of metabolic syndrome components [3-5]
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J Neural Transm Suppl 2007;(72):189-193