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In a trial supporting approval, people on the highest dose of Foundayo lost an average of 12% of their body weight over 72 weeks, compared with 0.9% for people taking a placebo

11 Heart failure, arrhythmia, syncope, and sudden death are less common manifestations

Data suggest the involvement of dopamine release from the VTA (44, 47, 50)

CURRENT ANTI-OBESITY PHARMACOTHERAPY Anti-obesity pharmacotherapy is indicated as an adjunct to lifestyle interventions in adults with a BMI 30 kg/m 2 or a BMI 27 kg/m 2 in patients with additional weight-related comorbidities

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