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whereas "open arm" behavior was shown in rats with lessened levels of anxiety

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They might be caused as a result of structural and chemical changes in the brain

In addition, altered metabolite concentrations after glucose administration also influence multiple metabolic pathways including glycolysis, gluconeogenesis, glycogenesis, amino acid metabolism, and lipid metabolism by regulating the abundance of substrates and products and the allosteric regulation of metabolic enzymes 14,16,17,18