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La activacin de EGFR por sus ligandos conduce a la activacin de una tirosincinasa citoplsmica que promueve la proliferacin a travs de varias vas de seales, como la de las MAP-cinasas (MAPK) o la de la fosfatidilinositol-3-OH cinasa (PI3K/ Akt)

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In ex vivo studies using isolated blood vessels, BPC-157 induces vasodilation through increased nitric oxide production, with effects blocked by endothelium removal or eNOS inhibition