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To explain why dopaminergic neurons in the substantia nigra pars compacta (SNpc) are destroyed in Parkinson's disease, there are two primary explanations

It does not cause photosensitivity (unlike retinoids), does not thin the skin (unlike corticosteroids), and does not require a tolerance-building period

Others have linked low glutathione levels to lack of sleep in animals and in people with certain sleep disorders

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A landmark 2009 study found that GHK-Cu reversed the gene expression of older skin cells to look more like young skin cells, upregulating collagen and downregulating inflammatory genes