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As limitaes atuais da pesquisa incluem a ausncia de ensaios clnicos randomizados de grande porte em humanos, uma compreenso ainda parcial dos mecanismos moleculares precisos e uma carncia de dados farmacocinticos detalhados em humanos

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The initial evidence consisted of case reports and small case series, but subsequent large retrospective cohort studies confirmed the association

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The Diagnostic and Statistical Manual (DSM) provides diagnosis criteria for both ASD and Attention Deficit Hyperactivity Disorder (ADHD)