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A related principle is worth noting at this point

Future studies focusing on younger asymptomatic carriers and age-matched controls may improve stratification and enable earlier detection of disease progression

Minimizing these effects often requires careful dosing and medical supervision

That means they come from individuals, not from research studies

For instance, SGLT2 inhibitors like Jardiance and Farxiga have been shown to protect against heart failure from heart disease and worsening kidney disease in people with Type 2 diabetes