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Given the established protective properties of both SGLT-2Is and GLP-1RAs on kidney function, this finding is unexpected if it truly represents the degree of fibrosis, suggesting that the observed changes in ADC may represent other changes in kidney microstructure

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Ascorbic acid decreased the incidence of kidney tumors by estradiol or diethylstilbesterol in hamsters due to decrease in the formation of genotoxic metabolites viz., diethylstilbesterol-4'-4"-qunione [68]

More research on these newer medications can help determine how they compare side-by-side for injection and oral form