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Together, these data demonstrate that metformin induces cell death in HCT116 and SW837 alone and in combination with radiation treatment, and that may be a contributing mechanism underlying the metformin-mediated radiosensitisation of HCT116 and SW837 cells

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MT-I and MT-II have various modifications compared to -MSH, affecting their affinity to the various MCRs and, thus, their potential effects

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