As with any supplement, moderation and informed use are key
GLP-1 receptor agonist molecules like semaglutide and tirzepatide are too large (4,100-4,800 daltons) to cross the skin barrier, which effectively blocks molecules above 500 daltons
One of the MDLs is centered on gastrointestinal injuries associated with these drugs, while the other, smaller MDL is focused on NAION and vision loss
Yilmaz-Ersan et al., 2016)
Tolerance varies between individuals, so you may find you can include moderate amounts of healthy fats without discomfort
The American Academy of Ophthalmology states that a direct causal link between GLP-1 medications and eye damage has not been firmly established