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Some researchers have reported unexpected pregnancies while on tirzepatide, likely because improved metabolic health can restore ovulation in women with weight-related anovulation

doi: 10.1016/J.EBIOM.2024.105284 105 Izzi-EngbeayaCJonesSCrustnaYMachenahalliPCPapadopoulouDModiMet al

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A notable finding from CagriSema trials: the GI side effect profile of the combination was similar to semaglutide monotherapy , not meaningfully worse