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Using an in vitro system of prostate cancer cell lines and patient-derived CAFs, this study visualized exosome uptake and noted that the uptake of these exosomes was followed by a decrease in cancer cell mitochondrial oxidative phosphorylation, concomitantly leading to an increase in glycolysis

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Each has distinct dosing schedulesranging from daily to weekly injectionsand slightly different efficacy and tolerability profiles

Since ascorbic acid can be metabolized non-enzymatically to oxalate , these inconsistencies in urinary oxalate measurement persist to this day [15, 23]