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TXNRD1 is one of the most investigated selenoproteins and regarded as one of the major antioxidant enzymes and redox regulators in mammalian cells

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Therefore, the crosstalk between LPO products such as 4-HNE and -catenin suggests that oxidative stress and lipid peroxidation are biphasic agents that can either contribute to pathological progression in, for example, normal tissues, or exert tumour -suppressive effects by masking oncogenic signals

Maternal hydroxytyrosol administration improves neurogenesis and cognitive function in prenatally stressed offspring