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Employer Strategies On-Demand Webinars SmithRx Key Takeaways GLP-1s are highly effective for diabetes and obesity but surged demand and costs, use up ~587% and list prices near $1,000/mo, forcing prior auths and spiking employer drug spend

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Oral versions may help, but adoption lags despite benefits for heart, metabolism, and liver

Compounded semaglutide is not FDA-approved, has not undergone FDA review for safety or effectiveness, and is not the same as, nor equivalent to, Ozempic or Wegovy

The association was still present when patients on medications for opioid, alcohol, or nicotine use disorder were excluded, with a 44% lower risk during active GLP-1 use and a 28% lower risk after discontinuation