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Sau et al

Participants continuing treatment with Zepbound MTD preserved all of their prior weight loss over the 1-year period, while those on the dose reduction maintained all but 5.6 kg on average

Their run splits improve for a while

The boxed warning for thyroid C-cell tumors applies to both semaglutide and tirzepatide based on rodent studies relevant for anyone with a personal or family history of medullary thyroid carcinoma or MEN2 syndrome

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