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Mol Pharm 10:23402349 Mata-Marin JA, Mendez-Cruz R, Arroyo-Anduiza CI, Mata-Marin LA, Gaytan-Martinez J, Asbun-Bojalil J (2013) Effect of antiretroviral therapy on inflammatory markers of endothelial dysfunction in HIV treatment-naive infected patients

452 Clinically, oral budesonide (9 mg daily) is safe and effective for clinical and endoscopic remission in patients with mild to moderate UC that is refractory to mesalazine

But for selected patients, thoughtful hormone evaluation may be part of a broader plan to support sleep, body composition, sexual health, energy, bone, mood, and quality of life

This mechanism was also confirmed in subsequent studies

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Obesity is a chronic condition, and the biological factors driving weight gain reassert themselves when medication ends