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In atherogenesis, endothelial dysfunction and oxidized lipids drive monocyte recruitment and foam-cell formation and ferroptotic susceptibility rises in PUFA-rich plaques when labile iron expands (Ouyang et al
Siemes H, Nau H, Schultze K, Wittfoht W, Drews E, Penzien J, Seidel U: Valproate (VPA) metabolites in various clinical conditions of probable VPA-associated hepatotoxicity
F., Arduini, A., Di, Liberato L., and Bonomini, M
It also contributes to accelerated skin aging and can lead to the development of skin cancer (114)
10.1016/j.immuni.2019.03.016 Immunity 48 HardyJ