In the central nervous system (CNS), GSH functions include maintenance of neurotransmitters, membrane protection, detoxification, metabolic regulation, and modulation of signal transduction
G.SimonsK
This has become evident mostly in recent years with the advent of single-cell RNA sequencing techniques, which have helped to unravel the vast heterogeneity and plasticity of this cell type ( Another important conceptual shift in the field of fibroblast research is the recognition that these cells can be drivers of disease, rather than mere responders to the inflammatory or pathogenic microenvironment
J.PufahlR
Since metabolites are the final downstream products of transcription and translation, they are closest to the phenotype ( To date, to identify biomarkers for the diagnosis and treatment response of MDD, lipids ( By profiling the serum metabolites of the patients with MDD and the control group, metabolites showing differences between the groups were identified as potential biomarkers
Benzodiazepine withdrawal can clearly be stressful but, strangely, in patients that I have tested, blood cortisol concentrations have been low
