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Reprod Fertil Dev 17:641650 Alwan S, Reefhuis J, Rasmussen SA, Olney RS, Friedman JM (2007) Use of selective serotonin-reuptake inhibitors in pregnancy and the risk of birth defects
Unlike conventional cellular and mammalian models, zebrafish offer distinct advantages for real-time live imaging, rapid genetic manipulation, and conserved immune and metabolic pathwaysmaking them particularly suitable for mechanistic studies of natural products and novel compound screening (Sukardi et al., 2011)
Mammalian target of rapamycin (mTOR), a serine/threonine (Ser/Thr) protein kinase, is a central controller of cell proliferation, growth and survival
Its effects on tendon healing appear mediated through increased expression of growth hormone receptor and upregulation of tendon-specific markers
These results guide personalized dosing and route selection
Reduced Inflammation : It modulates the bodys inflammatory response, helping to calm chronic inflammation at the source
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