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The lumen of the distal convoluted tubules was large and bordered by simple cubical cells with sphere nuclei in the middle or at the apex of the tubule walls (Figure 7A)

10.1161/atvbaha.120.315506 29 GrisantiS.CosentiniD.TovazziV.BianchiS.LazzariB.ConsoliF.et al (2018)

Theres also the issue of tolerance

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