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Sleep disruption changes the microbiome, as is shown in experiments where alterations in gut bacterial profiles were found in mice with circadian rhythm mutations or rats with chronic sleep deprivation (Chandra et al., 2023)

Furthermore, Luo et al

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cDNA cloning and expression analysis of genes encoding GSH synthesis in roots of the heavy-metal accumulator Brassica juncea L.: Evidence for Cd-induction of a putative mitochondrial gamma-glutamylcysteine synthetase isoform

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The reconstitution math and per-IU equivalences in this article describe physical concentrations in a vial, not human therapeutic doses