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Similarly, in the current study, DIO mice from both groups that were switched from WD to LD exhibited higher Bacteroidetes and significantly lower Firmicutes relative abundances compared to DIO mice maintained on WD (WD controls

Physiology, hypothalamus

This wind-up state is believed to be related to neuroplasticity which is mediated by the N-Methyl-D-aspartate (NMDA) receptors located in the postsynaptic membrane in the dorsal horn of the spinal cord