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Recent data from insurance claims indicates that 30% of patients stop treatment within a month, well before any clinically meaningful results could be achieved

Main text Modern GLP-1 receptor agonists and co-agonists (GLP-1 medicines) such as liraglutide, dulaglutide semaglutide, and the GLP-1R/glucose dependent insulinotropic polypeptide receptor (GIPR) co-agonist tirzepatide, were initially developed for the treatment of type 2 diabetes (T2D) due to their actions to increase insulin and decrease glucagon secretion and slow gastric emptying through effects on the pancreas and brain

A Retatrutide dose escalation schedule refers to the stepwise way a provider increases treatment over time, rather than a single fixed timeline that applies to every patient

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Semaglutide has been on the market longer and has more extensive clinical experience and usage history