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10.1152/ajpcell.2001.281.6.C1757 145 NazioF.StrappazzonF.AntonioliM.BielliP.CianfanelliV.BordiM.et al (2013)

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Dehydration is a particular concern in older adults

Two letters cited failure to submit an Investigational New Drug (IND) application for clinical investigations with an investigational new drug, per 21 CFR 312.2(a)

These drugs are not readily available to doctors or the general public